Women with cystic fibrosis are expected to have safe and effective fertility treatment

Release date: 2009-08-13

A recent study at the 25th European Society for Human Reproduction and Embryology in Amsterdam showed that women with cystic fibroids can be born through fertility treatment and have no long-term adverse effects on their children or pregnant women. Until now, cystic fibromas have been linked to death, and they have died in their teens. Now, with good treatment conditions, people can live longer and even have their own family. This is no longer a case. However, women with cystic fibroma also face fertility problems. Cystic fibroma can lead to infertility. First, the use of reproductive assistive technology to conduct research and systematic evaluation of infertility patients with cystic fibroma. The study selected 24 women who visited the H??pital Cochi Saint Vincent de Paul from 1998 to 2008. After a health assessment of them, three women abandoned treatment due to certain medical problems and six were still under evaluation. The remaining 15 were treated with fertility treatment. Dr Sylvie Epelboin, who is in charge of the trial, is an obstetrician and coordinator of the Paris-based ART-CF disease network. He pointed out: "Women with cystic fibroids interfere with nature due to thick cervical mucus. Pregnancy. However, this condition can be solved by intrauterine insemination and in vitro fertilization. Fertility treatment depends on women's good lung and nutritional status, and mothers who are worried about their child's welfare may be seriously ill, even need to do lung transplantation or even death. Women do not have cystic fibroid gene mutations in their partners. They have normal indicators except for those who have not successfully conceived. These women are between the ages of 24 and 36. Doctors first take intrauterine insemination and 15 successful pregnancies A woman undergoes in vitro fertilization after fertilization in the womb and is pregnant after a frozen embryo transfer. Another woman receives a donated egg and becomes pregnant because of an ovarian decline. Overall, 13 out of 15 women are pregnant, 17 times pregnant, 12 live births, 2 pregnant, 3 abortions. All women observed, except one, can not have a Caesarean section Give birth in case. Although half of them have diabetes during pregnancy and mild lung function decline, all mothers are very healthy. Newborns are born around 37 weeks on average, and only 4 newborns are born with light weight. 2500 grams (born children range from 1910 grams to 3500 grams). None of the newborns weighed less than the minimum weight (1500 grams). 5 newborns have been breastfed. All children, 7 females and 5 males, aged 10 years old It is healthy for a month. Dr Epelboin said: Our findings are good news for women with cystic fibroids. Assisted reproductive technology is a promising choice for them, whether for themselves or There is no medical risk or death for their children. Moreover, for young women with growing cystic fibroma, assisted reproductive technology improves their quality of life and makes them possible to have the next generation. Children provide mature advice and support from the family. These recommendations also apply to infertile men with cystic fibroma who also need assisted reproductive technology through cytoplasm Internal sperm injection (injecting sperm directly into the egg) is given to the child. However, she warns that professional assisted reproductive technology, the maternal team's mutual cooperation is essential, and they need to take care of the woman before and after pregnancy. The general health status of these women requires careful assessment, and they require medical, genetic, and ethical counselling before the treatment of gestation. The treatment of induced ovulation must achieve moderate response and a single pregnancy, and close monitoring of prenatal care is necessary. The reason why a single pregnancy is also important during pregnancy is because the tension caused by multiple pregnancies affects the heart and lungs, nutritional balance, etc., and may also cause the risk of premature birth due to cough involvement in the abdomen. In addition, the single pregnancy is for them after the care and Medical follow-up is easier, and diabetes and glucose intolerance often occur in patients with cystic fibroma due to their pancreatic lesions. Some patients with cystic fibroma have diabetes before pregnancy, so they need to control insulin levels before they become pregnant. In addition, some patients have elevated blood glucose during pregnancy, ie, high blood sugar during pregnancy. With the joint efforts of Dr Dominique Hubert's pulmonary specialist and network coordination, Dr Epelboin is conducting an investigation to track cystic fibroma mothers, couples and children, as well as women who receive assisted reproductive treatment but no serious genetic disease. “We want to see how they view the social welfare of children living in families where the mother is cf from an ethical perspective. What are the expectations or needs of these mothers for transplants and the limited life they have for families and children? Impact. This can only be achieved through long-term monitoring, and we can be sure that our initial conclusions are optimistic," she said. Meditech Medical Network

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