Traditional Chinese medicine formula granules are made by using modern production technology to extract, concentrate, dry and granulate single-flavored traditional Chinese medicine decoction pieces, which are safe and convenient to use. In recent years, with the continuous introduction of favorable national policies, such as the publication of the Technical Requirements for Quality Control and Standard Formulation of Chinese Medicine Formulas (Draft for Comment), the Outline of Strategic Planning for Development of Traditional Chinese Medicine (2016-2030) strengthens Chinese medicine formula granules. The standard formulation and quality management of the Chinese medicine formula granule market is constantly expanding. According to relevant data, the overall size of the Chinese medicine formula pellet market will increase to 18 billion yuan in 2018. Faced with the huge market cakes, various pharmaceutical companies are eager to make a fuss about the market of deep-growing traditional Chinese medicine formula pellets.
The author has learned in the access to information that nearly 30 pharmaceutical companies have recently been approved as provincial-level scientific research specials/pilot enterprises. Major enterprises have seized the market of Chinese medicine formula granules. Then, in this round of competition, have pharmaceutical equipment companies also made great efforts to prepare advanced technologies and equipment for pharmaceutical companies?
It is understood that traditional Chinese medicine formula granules such as Dangshen formula granules and licorice formula granules are obtained by extracting, concentrating, drying and granulating the whole ingredients of single-flavored traditional Chinese medicine decoction pieces. Therefore, major pharmaceutical companies must purchase pulverizers in the market competition. Mixing machines, granulators, packaging and sealing machines, and other pharmaceutical equipment, and with the increasingly fierce market competition and the increasingly strict control of the quality of traditional Chinese medicine formulas, advanced technology, high-quality equipment will become more and more As sought after by major pharmaceutical companies, as early as 2012, Kangmei Pharmaceutical has invested in the production automation of Chinese medicine formula pellets and online quality monitoring technology transformation projects.
Compared with the traditional Chinese medicine decoction, the traditional Chinese medicine formula granules adopt large-scale, automatic, scientific and standardized management, which can better ensure the stability of the drug effect. In this process, what the pharmaceutical equipment needs to do is to improve the technical level of the equipment, so as to better meet the production requirements of the Chinese medicine formula particles. Take the granulator used in the production of traditional Chinese medicine granules as an example. What companies need to do is actively carry out technological innovation research and development to ensure that the equipment can efficiently produce high-quality granules and improve the stability, disintegration and dissolution of the granules. Sex.
The author was informed that with the continuous growth of the Chinese medicine formula granule market, many granulator companies have increased their technical input and combined with the actual situation of traditional Chinese medicine formula particles to find new solutions to solve key problems for pharmaceutical companies. For example, Changzhou Lima Dry Production LG dry granulator uses a new pressure roller control technology to adjust the process parameters such as processing volume and sheet density by adjusting the physical fluctuation between different materials and different batches of the same batch of materials. The pressure of the press roll, the rotational speed, etc. can be precisely and repeatedly adjusted, thereby ensuring the production efficiency of the particles as well as the quality and stability of the particles.
Traditional Chinese medicine formula granules have the advantages of high purity, remarkable curative effect, small adverse reactions and high scientific and technological content. They are a major breakthrough in the development of Chinese medicine and the creation of new situations. However, compared with traditional Chinese medicine decoction pieces, the composition of traditional Chinese medicine formula is complex. Therefore, each Chinese herbal medicine needs strict control from raw material quality control, production process, process control, terminal quality control or quality inspection, and pharmaceutical equipment is required for the production of traditional Chinese medicine formula pellets. The key equipment, the quality of the equipment and the technology are directly related to the quality and efficacy of the traditional Chinese medicine formula. Pharmaceutical companies should carefully select equipment when they enter the Chinese medicine formula pellet market. For example, in addition to the granulator mentioned above, the extraction equipment is also one of the objects that need to be selected.
It is understood that in the extraction equipment, the application of the ultrasonic countercurrent extraction unit effectively improves the extraction efficiency. According to the relevant technical personnel, the ultrasonic countercurrent extraction unit is a continuous countercurrent process, the medicinal material is automatically and quantitatively input from the feed inlet, and the solvent is metered into the liquid from the inlet, and the leaching solution and the medicinal material form an opposite continuous countercurrent leaching process. “Using ultrasonic countercurrent extraction equipment, the extraction of active ingredients is more complete and the extraction time is shorter.â€
Traditional Chinese medicine is a gem of the Chinese nation, and the promotion and use of traditional Chinese medicine formula granules integrates tradition into modern inheritance. It expands the space in terms of convenience, efficiency, quality of medicine or method of use. It is understood that after years of scientific research accumulation, China's pharmaceutical equipment enterprises have made great progress, Chinese medicine formula particles have a solid equipment foundation, but in order to promote the Chinese medicine formula particles into the fast track of development, pharmaceutical machinery and equipment enterprises still need to break through the technical bottleneck And combined with the actual demand of traditional Chinese medicine formula pellets to gradually improve the equipment, to promote more reasonable and more humane equipment, so as to better meet the needs of Chinese medicine formula pellet production enterprises, help pharmaceutical companies solve production problems.
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