99% Purity Pharmaceuticals Intermediate Roflumilast for Respiratory Disease

• Model NO.: 162401-32-3
• Customized: Non-Customized
• Suitable for: Adult
• Purity: >99%
• Synonyms: by 217;Byk 20869;Daxas;
• MW: 403.21
• Einecs: 223-583-8
• Grade: Pharma Grade
• Package: Discreet
• Transport Package: Accoding to Every Customers′ Requirements
• Origin: China

• Powder: No
• Certification: GMP, HSE, ISO 9001, USP, BP
• State: Liquid
• Product Name: Roflumilast
• CAS: 162401-32-3
• Mf: C17h14cl2f2n2o3
• Appearance: White Powder
• Usage: Antiasthmatic; in Treatment of Chronic Obstructive
• Trademark: Saichuang
• Specification: qualified
• HS Code: 3001200010

99% Purity Pharmaceuticals Intermediate Roflumilast For Respiratory Disease

 

Description

Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. Due to its selective inhibition of the PDE4 isoenzyme in lung cells, roflumilast is indicated for the management of chronic obstrtuctive pulmonary disease (COPD) exacerbations. Treatment with Roflumilast is associated with an increase in psychiatric adverse reactions,
including suicide and suicidal attempts.

Application

Roflumilast can be used for the prevention and treatment of respiratory disease, and used for the treatment of severe chronic obstructive pulmonary disease (COPD) and excessive mucus cough bronchitis, asthmatic bronchitis, bronchial asthma, respiratory tract associated with abnormal secretion of acute and chronic bronchitis, air sacculitis, etc.

Chronic obstructive pulmonary disease (referred to as "COPD"), is chronic lung disease that characterized by incompletely reversible airflow obstruction. It is usually manifested clinically recurrent cough, sputum, dyspnea and other symptoms. That usually shows progressive progress features, including the vast majority of chronic bronchitis and emphysema. As the disease progresses, it will lead to airway remodeling, and ultimately develop to irreversible airflow obstruction, or coexist with asthma overlap. Therefore, improving the control of airflow obstruction and inflammation is the main goal of drug research at home and abroad.

Chronic obstructive pulmonary disease (COPD) is one of progressive and life-threatening lung disease and one of the human health "killer". It makes dyspnea, loss of activity. The disease typically includes chronic bronchitis and emphysema. It is estimated that about 210 million people worldwide suffer from the disease, and COPD will become the third largest cause of death in the world by 2020. Based on the conclusions of the US National Heart, Lung, and Blood Institute, smoking is the major risk factor for COPD.

How should this medicine be used?

Roflumilast comes as a tablet to take by mouth. It is usually taken with or without food once a day. Take roflumilast at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take roflumilast exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Do not use roflumilast to treat sudden attacks of breathing problems. Talk to your doctor about the use of other medications to treat symptoms of a sudden breathing problem.

Roflumilast may control COPD but does not cure it. Continue to take roflumilast even if you feel well. Do not stop taking roflumilast without talking to your doctor.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with roflumilast and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the manufacturer's website to obtain the Medication Guide.

Function And Usage

Roflumilast is a selective phosphodiesterase 4 (PDE4) (IC50 = 0.8 nM) inhibitor. Inhibition of PDE4 prevents the hydrolysis of phosphodiesters, which play a key role in signal transduction. This compound has anti-inflammatory properties and is particularly effective at reducing inflammation in lung tissue.

Advantage

1) Rich experience
We specialize in this field for many years,our pharmaceutical raw materials exported to overseas, to Europe,
Africa, Asia, Americas and other country, and we have got very good feedback from our customers,and Established long friendly relations of cooperation.

2) Great quality, purity and favorable
Good quality is one of our secret success, welcome order the samples.

3) Safest and fastest delivery
We have Adequate stock,and can arranged within 24 hours when receive the payment.Tracking number would be informed quickly after shipment.
We have special way could ship 2kg to 20tons products a time. We offer melting powder into liquid service. And
ship the liquid in special bottles.

4) Good after-sales service
Tell the package update asap, and will try best solve when customer encountered various problems!Everything is for customers.
Our products and services will focus on the largest customer demand, We hold the greatest enthusiasm and
sincere cooperation with each customer.
All in all, high quality, best service, security shipping and competitive price are our perpetual  pursuance. 
 

 

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