U.S. Research Reports 70% of Early Breast Cancer Patients Needs No Chemotherapy

According to Hong Kong's "Eastern Net" reported on June 4, the US medical community said on the 3rd that 70% of patients with early breast cancer after removal of the tumor, do not need to receive chemotherapy will not affect the survival rate, greatly reducing the patient's unnecessary pain. The results of the study were published at the annual meeting of the American Society for Clinical Oncology (ASCO) and also published in the New England Medical Journal.

So far, if a woman is diagnosed with a hormonal receptor positive, HER2-negative breast cancer, if the condition is still in an early stage where the cancer cells have not spread to the lymph nodes, it is often impossible to determine whether or not to undergo hormonal therapy while undergoing chemotherapy. Reduce the risk of cancer cell proliferation or recurrence. However, chemotherapy can cause problems such as vomiting, fatigue, infertility, and even leukemia, which makes the patient miserable.

Afterwards, the doctor will use Oncotype Dx to make a decision: If the patient gets more than 25 points, the representative must receive chemotherapy to prevent the recurrence of the disease; if less than 10 points, there is no need to receive chemotherapy.

The study was led by the Einstein School of Medicine in New York City. It was targeted at about 10,000 women earlier, and patients with a median recurrence score of 11 to 25 were included in the study. The doctor randomized patients between the ages of 18 and 75 to receive hormonal therapy plus chemotherapy and hormonal therapy only. The results showed that the 9-year survival rate of both groups was close to 94%, and there was no significant difference.

Kathy Albain, a co-author of the study and an oncologist at Loyola Medicine, described this pioneering study as allowing doctors to rest assured that about 70% of patients in this most common form of breast cancer Without chemotherapy: "For countless women and doctors, the time of uncertainty is over."

Alistair Ring, Royal Marsden Hospital in London, United Kingdom, said that the UK clinic may change the treatment of breast cancer from the 4th. (Internship Editor: Zhou Simin Reviewer: Tian Ruizhe)


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