In 2015, the Obama administration promulgated the “ Precision Medical Planâ€. In March 2016, the Ministry of Science and Technology of China also included precision medicine in key research and development programs. The policy level encouragement of precision medicine pushed up the heat of the industry and served as the gene for precision medical leaders. The sequencing industry is also hot. From the perspective of patents, this article strives to comprehensively explain the development of the gene sequencing industry.
Core points:
1. Currently, the exporting countries of high-end sequencing equipment on the market are mainly concentrated in the United States, while China is a large demanding country in the genetic sequencing market;
2. The number of patents related to gene sequencing accepted in China has accumulated to more than 20,000, the number of which is second only to the United States;
3. In terms of applications, the global research of gene sequencing also focuses on reproductive health and tumor diagnosis and treatment, and other medical fields and non-medical research have not made major breakthroughs.
At the beginning of 2013, Hollywood famous movie star Angelina Jolie discovered the risk of breast cancer after she was at high risk and removed the breast to prevent the disease. Before this, Apple's godfather Steve Jobs also used the whole genome after the diagnosis of pancreatic cancer. Sequencing to find tumor genes for a more accurate medication plan. The celebrity effect brings gene sequencing and precision medicine to the public's field of vision.
In early 2015, Obama publicized the US "Precision Medical Plan (PMI)" and said that this will bring about changes in the health care field. In March 2016, the Ministry of Science and Technology of China issued the “Notice on the publication of the 2016 National Project Application Guidelines for Key Medical Research and Development Programs, and the “Precise Medical Research†was listed as one of the priority projects in 2016. And support precision medicine based on gene sequencing. In April 2016, the National Development and Reform Commission issued the “Response on the Construction of the First Batch of Gene Detection Technology Application Demonstration Centersâ€, officially approving the construction plans of 27 provinces and municipalities on the application of genetic testing technology demonstration centers.
Seeing the development of gene sequencing under such a policy dividend, few people may think that as early as February 2014, the National Food and Drug Administration of the State Food and Drug Administration has issued a paper to inform the full stop of the industry-deficient gene sequencing clinical Application; and just four months later, the State Food and Drug Administration approved the second generation of gene sequencing diagnostic products of Shenzhen Huada Gene Company for the first time. This roller coaster-like industry change has finally led to the industry's rectification and multi-sectoral joint supervision, and is now thriving under various policy dividends.
First, the introduction of the gene sequencing industry
1. Gene sequencing industry chain
First, let's take a look at the industry chain of gene sequencing:
(1) At the top of the industrial chain are genetic sequencing instruments and consumable reagents. The major foreign companies are Illumina, Life Tech and Roche; domestic companies take the form of cooperation with foreign companies, the main companies are Huada Gene, Berry and Kang and Daan genes; the companies engaged in independent research and development mainly include Zixin Pharmaceutical (in cooperation with the Institute of Genomics of the Chinese Academy of Sciences).
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