Bringing 3 people with DNA to cause controversy or "genetically babies"
September 30, 2016 Source: Yangguang Network
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Everyone can only have a pair of biological parents, but now this inherent concept has been broken by American scientists. According to the BBC, a child carrying three genetic genes was born in April this year. Now he is 5 months old and very healthy. .
At the time of the birth check, the doctor found that the DNA of the mother of the baby boy was genetically deficient and was likely to cause brain disease in the baby. So with the consent of the couple, the medical team replaced the genetics of a female donor. Mom's defect gene. What gene is replaced? What is the principle?
Yin Wei, CEO of Huada Gene: There is a nucleus in the fertilized egg, which carries about 99.9% of the genes in the nucleus, but there is also a gene that is about 0.1% or one thousandth of the gene is not from the nucleus. It has special organelles called mitochondria in the fertilized egg, which is equivalent to the engine of each cell and is responsible for energy metabolism. The source of mitochondria inheritance can only be the mother, which is brought in the egg.
Half of any one's genes are from Dad, half of them are from mothers, and mothers are a little more than fathers, including mitochondrial genes.
Why do three people have a child? The mother's nucleus gene has no problem, but her mitochondrial gene has problems, which will cause her child to develop a mitochondrial disease after birth. It is a genetic disease. This technique uses another mother's normal mitochondria to replace the mother's problematic mitochondria, which is equivalent to putting the three human cells together.
The 99.9% of the baby's gene is still from his parents, and only 0.01% of the genes are from a third person, but there is no controversy both legally and ethically. First, the US government does not recognize the medical technology. In order to avoid legal disputes, the US medical research team went to Mexico without a law to ban the technology to complete the gene replacement work. Second, some conservative media have begun to discuss, who is his child? Will future genetic modification be abused? Whether our next generation will be genetically modified babies.
As a genetic worker, how do you view these ethical controversies?
Yin Wei: It is equivalent to transferring another person to your gene, which has caused some people's concerns. If a person puts on a prosthetic, is it another transplant? This is impossible two or three hundred years ago. It is very convenient now. Transplanting the heart of others and transplanting the cornea, is this another transformation? At present, these are ethically no problem. A lot of technological progress and ethics are not static.
This child is still mys after all, although I use one thousandth of the gene of the outsider, but after all, 99.9% is my father, mother, to the greatest extent, this child is born he is good, this decision is not in the hospital Nor is it in any commercial company, and in this pair of parents, the parents have the right to decide whether my child is defective or not defective, or I will help him to fix it.
Technology is far from a problem. In fact, the choice of parents is the most important. Even if I know that my child is born with defects, I insist on giving birth to him. I think it is also the personal choice of the family. This choice cannot be kidnapped with the ethics of the group. of.
On this basis, I think that the corresponding technology, in addition to using other people's mitochondria, I can also use genetic editing methods to modify our life code, this whole challenge to human society, I think it is a question that needs to be discussed, maybe We can't simply say that we will follow the market launch or not. It may take everyone to get in touch with such a point of view before it is possible to bring such a technology to the end, and ultimately it will bring trouble to us.
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